chromosome breakage_Palb2<tm1.1Dli>/Palb2<tm1.1Dli>,Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>,Cd19<tm1(cre)Cgn>/Cd19<+>

http://metadb.riken.jp/0004028I129P2OlaHsd129S4SvJaeSorC57BL6Palb2tm11DliPalb2tm11DliTrp53bp1tm1JcTrp53bp1tm1JcCd19tm1creCgnCd19Cd19tm1creCgnTrp53bp1tm1JcCd19Palb2tm11Dli

chromosome breakage_Palb2<tm1.1Dli>/Palb2<tm1.1Dli>,Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>,Cd19<tm1(cre)Cgn>/Cd19<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53 binding protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1351320
• partner and localizer of BRCA2
  http://metadb.riken.jp/db/mgi_rdf/MGI:3040695
• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Palb2<tm1.1Dli>/Palb2<tm1.1Dli>,Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>,Cd19<tm1(cre)Cgn>/Cd19<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<tm1(cre)Cgn>|Trp53bp1<tm1Jc>|Cd19<+>|Palb2<tm1.1Dli>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• chromosome breakage
  http://purl.obolibrary.org/obo/MP_0004028

文献

http://purl.org/net/cito/citesAsAuthority

• Christian. Bowman-Colin, et.al., Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/23657012