increased compact bone thickness_Smad4<tm2.1Cxd>/Smad4<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

http://metadb.riken.jp/0004148I129S6SvEvTacC57BL6JCD1Smad4tm21CxdSmad4TgSp7tTAtetOEGFPcre1Amc0Smad4TgSp7tTAtetOEGFPcre1AmcSmad4tm21Cxd

increased compact bone thickness_Smad4<tm2.1Cxd>/Smad4<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:3689349
• SMAD family member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:894293

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Smad4<tm2.1Cxd>/Smad4<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Smad4<+>|Tg(Sp7-tTA,tetO-EGFP/cre)1Amc|Smad4<tm2.1Cxd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6J * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased compact bone thickness
  http://purl.obolibrary.org/obo/MP_0004148

文献

http://purl.org/net/cito/citesAsAuthority

• Valerie S. Salazar, et.al., Embryonic ablation of osteoblast Smad4 interrupts matrix synthesis in response to canonical Wnt signaling and causes an osteogenesis-imperfecta-like phenotype., Journal of cell science, 2013, 126
  http://rdf.ncbi.nlm.nih.gov/pubmed/24006258