increased basal cell carcinoma incidence_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0004208I129P2OlaHsd129S1Sv129X1SvJBALBcC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1Hahn

increased basal cell carcinoma incidence_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• patched 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:105373

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>|Gt(ROSA)26Sor<+>|Ptch1<tm1Hahn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased basal cell carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0004208

文献

http://purl.org/net/cito/citesAsAuthority

• Arne. Zibat, et.al., Time-point and dosage of gene inactivation determine the tumor spectrum in conditional Ptch knockouts., Carcinogenesis, 2009, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/19321799