increased cellular sensitivity to ionizing radiation_Rif1<Gt(XT0278)Wtsi>/Rif1<Gt(XT0278)Wtsi>

http://metadb.riken.jp/0004227I129P2OlaHsdCD1MF1Rif1GtXT0278WtsiRif1GtXT0278WtsiRif1GtXT0278Wtsi

increased cellular sensitivity to ionizing radiation_Rif1<Gt(XT0278)Wtsi>/Rif1<Gt(XT0278)Wtsi>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• replication timing regulatory factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1098622

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rif1<Gt(XT0278)Wtsi>/Rif1<Gt(XT0278)Wtsi>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rif1<Gt(XT0278)Wtsi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * CD-1 * MF1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cellular sensitivity to ionizing radiation
  http://purl.obolibrary.org/obo/MP_0004227

文献

http://purl.org/net/cito/citesAsAuthority

• J Ross. Chapman, et.al., RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection., Molecular cell, 2013, 49
  http://rdf.ncbi.nlm.nih.gov/pubmed/23333305