increased cellular sensitivity to ionizing radiation_Ing1<Gt(OST206270)Lex>/Ing1<Gt(OST206270)Lex>,Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0004227I129S5SvEvBrd129S7SvEvBrdC57BL6Ing1GtOST206270LexIng1GtOST206270LexTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdIng1GtOST206270Lex

increased cellular sensitivity to ionizing radiation_Ing1<Gt(OST206270)Lex>/Ing1<Gt(OST206270)Lex>,Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• inhibitor of growth family, member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1349481
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ing1<Gt(OST206270)Lex>/Ing1<Gt(OST206270)Lex>,Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brd>|Ing1<Gt(OST206270)Lex>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cellular sensitivity to ionizing radiation
  http://purl.obolibrary.org/obo/MP_0004227

文献

http://purl.org/net/cito/citesAsAuthority

• Andrew H. Coles, et.al., Deletion of p37Ing1 in mice reveals a p53-independent role for Ing1 in the suppression of cell proliferation, apoptosis, and tumorigenesis., Cancer research, 2007, 67
  http://rdf.ncbi.nlm.nih.gov/pubmed/17332334