Andrew H. Coles, et.al., Deletion of p37Ing1 in mice reveals a p53-independent role for Ing1 in the suppression of cell proliferation, apoptosis, and tumorigenesis., Cancer research, 2007, 67

http://rdf.ncbi.nlm.nih.gov/pubmed/17332334

Andrew H. Coles, et.al., Deletion of p37Ing1 in mice reveals a p53-independent role for Ing1 in the suppression of cell proliferation, apoptosis, and tumorigenesis., Cancer research, 2007, 67

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ing1<Gt(OST206270)Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3700145

class

http://purl.org/net/cito/citesAsAuthority

• Ing1<Gt(OST206270)Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3700145

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased B cell derived lymphoma incidence_Ing1<Gt(OST206270)Lex>/Ing1<+>
  http://metadb.riken.jp/0002023I129S5SvEvBrdC57BL6Ing1GtOST206270LexIng1Ing1Ing1GtOST206270Lex
• increased B cell derived lymphoma incidence_Ing1<Gt(OST206270)Lex>/Ing1<Gt(OST206270)Lex>
  http://metadb.riken.jp/0002023I129S5SvEvBrdC57BL6Ing1GtOST206270LexIng1GtOST206270LexIng1GtOST206270Lex
• increased thymocyte apoptosis_Ing1<Gt(OST206270)Lex>/Ing1<Gt(OST206270)Lex>
  http://metadb.riken.jp/0009541I129S5SvEvBrdC57BL6Ing1GtOST206270LexIng1GtOST206270LexIng1GtOST206270Lex
• increased cellular sensitivity to ionizing radiation_Ing1<Gt(OST206270)Lex>/Ing1<Gt(OST206270)Lex>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0004227I129S5SvEvBrd129S7SvEvBrdC57BL6Ing1GtOST206270LexIng1GtOST206270LexTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdIng1GtOST206270Lex
• increased cell proliferation_Ing1<Gt(OST206270)Lex>/Ing1<Gt(OST206270)Lex>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0000351I129S5SvEvBrd129S7SvEvBrdC57BL6Ing1GtOST206270LexIng1GtOST206270LexTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdIng1GtOST206270Lex
• increased cell proliferation_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0000351I129S7SvEvBrdTrp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• decreased thymocyte number_Ing1<Gt(OST206270)Lex>/Ing1<Gt(OST206270)Lex>
  http://metadb.riken.jp/0000715I129S5SvEvBrdC57BL6Ing1GtOST206270LexIng1GtOST206270LexIng1GtOST206270Lex
• decreased body weight_Ing1<Gt(OST206270)Lex>/Ing1<Gt(OST206270)Lex>
  http://metadb.riken.jp/0001262I129S5SvEvBrdC57BL6Ing1GtOST206270LexIng1GtOST206270LexIng1GtOST206270Lex
• increased cellular sensitivity to ionizing radiation_Ing1<Gt(OST206270)Lex>/Ing1<Gt(OST206270)Lex>
  http://metadb.riken.jp/0004227I129S5SvEvBrdC57BL6Ing1GtOST206270LexIng1GtOST206270LexIng1GtOST206270Lex
• increased fibroblast apoptosis_Ing1<Gt(OST206270)Lex>/Ing1<Gt(OST206270)Lex>
  http://metadb.riken.jp/0013501I129S5SvEvBrdC57BL6Ing1GtOST206270LexIng1GtOST206270LexIng1GtOST206270Lex
• abnormal cell physiology_Ing1<Gt(OST206270)Lex>/Ing1<Gt(OST206270)Lex>
  http://metadb.riken.jp/0005621I129S5SvEvBrdC57BL6Ing1GtOST206270LexIng1GtOST206270LexIng1GtOST206270Lex
• increased fibroblast proliferation_Ing1<Gt(OST206270)Lex>/Ing1<Gt(OST206270)Lex>
  http://metadb.riken.jp/0011703I129S5SvEvBrdC57BL6Ing1GtOST206270LexIng1GtOST206270LexIng1GtOST206270Lex
• decreased cellular sensitivity to ionizing radiation_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0004228I129S7SvEvBrdTrp53tm1BrdTrp53tm1BrdTrp53tm1Brd
• decreased apoptosis_Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0006043I129S7SvEvBrdTrp53tm1BrdTrp53tm1BrdTrp53tm1Brd

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased cellular sensitivity to ionizing radiation in RBRC09248
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010231
• increased cell proliferation in RBRC09248
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010219