increased cellular sensitivity to ionizing radiation_Mre11a<tm1Dof>/Mre11a<tm2.1Dof>

http://metadb.riken.jp/0004227I129S6SvEvTacMre11atm1DofMre11atm21DofMre11atm1DofMre11atm21Dof

increased cellular sensitivity to ionizing radiation_Mre11a<tm1Dof>/Mre11a<tm2.1Dof>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• MRE11A homolog A, double strand break repair nuclease
  http://metadb.riken.jp/db/mgi_rdf/MGI:1100512

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mre11a<tm1Dof>/Mre11a<tm2.1Dof>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mre11a<tm1Dof>|Mre11a<tm2.1Dof>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cellular sensitivity to ionizing radiation
  http://purl.obolibrary.org/obo/MP_0004227

文献

http://purl.org/net/cito/citesAsAuthority

• Jeffrey. Buis, et.al., Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation., Cell, 2008, 135
  http://rdf.ncbi.nlm.nih.gov/pubmed/18854157