increased cellular sensitivity to ionizing radiation_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>

http://metadb.riken.jp/0004227I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa

increased cellular sensitivity to ionizing radiation_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sirtuin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2135607

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sirt1<tm1Fwa>/Sirt1<tm1Fwa>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sirt1<tm1Fwa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129S6/SvEvTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cellular sensitivity to ionizing radiation
  http://purl.obolibrary.org/obo/MP_0004227

文献

http://purl.org/net/cito/citesAsAuthority

• Hwei-Ling. Cheng, et.al., Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/12960381