Hwei-Ling. Cheng, et.al., Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100

http://rdf.ncbi.nlm.nih.gov/pubmed/12960381

Hwei-Ling. Cheng, et.al., Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Sirt1<tm2Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2677357
• Sirt1<tm1Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2677354
• Sirt1<tm3Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4359275
• Sirt1<tm2.1Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2677369

class

http://purl.org/net/cito/citesAsAuthority

• Sirt1<tm2Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2677357
• Sirt1<tm1Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2677354
• Sirt1<tm3Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4359275
• Sirt1<tm2.1Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2677369

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal eye morphology_Sirt1<tm2Fwa>/Sirt1<tm2Fwa>
  http://metadb.riken.jp/0002092I129Sv129S6SvEvTacSirt1tm2FwaSirt1tm2FwaSirt1tm2Fwa
• perinatal lethality, incomplete penetrance_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0011090I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• ventricular septal defect_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0010402I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• abnormal eye morphology_Sirt1<tm2.1Fwa>/Sirt1<tm2.1Fwa>
  http://metadb.riken.jp/0002092I129Sv129S6SvEvTacSirt1tm21FwaSirt1tm21FwaSirt1tm21Fwa
• oligozoospermia_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0002687I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• abnormal eye development_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0001286I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• disorganized retinal inner nuclear layer_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0008512I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• increased cellular sensitivity to ionizing radiation_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0004227I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• exencephaly_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0000914I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• decreased embryo size_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0001698I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• postnatal lethality, incomplete penetrance_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0011086I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• decreased body size_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0001265I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• abnormal retinal photoreceptor morphology_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0001004I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• abnormal retinal layer morphology_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0003727I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• abnormal heart development_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0000267I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• atrial septal defect_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0010403I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• microphthalmia_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0001297I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• disorganized retinal outer nuclear layer_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0008516I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• abnormal atrioventricular valve morphology_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0002745I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• abnormal eye morphology_Sirt1<tm1Fwa>/Sirt1<tm1Fwa>
  http://metadb.riken.jp/0002092I129Sv129S6SvEvTacSirt1tm1FwaSirt1tm1FwaSirt1tm1Fwa
• atrial septal defect_Sirt1<tm2Fwa>/Sirt1<tm2Fwa>
  http://metadb.riken.jp/0010403I129Sv129S6SvEvTacSirt1tm2FwaSirt1tm2FwaSirt1tm2Fwa