decreased cellular sensitivity to ionizing radiation_Lig4<tm1Icrf>/Lig4<tm1Icrf>,Mre11a<tm1Jpt>/Mre11a<tm1Jpt>

http://metadb.riken.jp/0004228I129129S7SvEvBrdLig4tm1IcrfLig4tm1IcrfMre11atm1JptMre11atm1JptMre11atm1JptLig4tm1Icrf

decreased cellular sensitivity to ionizing radiation_Lig4<tm1Icrf>/Lig4<tm1Icrf>,Mre11a<tm1Jpt>/Mre11a<tm1Jpt>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ligase IV, DNA, ATP-dependent
  http://metadb.riken.jp/db/mgi_rdf/MGI:1335098
• MRE11A homolog A, double strand break repair nuclease
  http://metadb.riken.jp/db/mgi_rdf/MGI:1100512

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lig4<tm1Icrf>/Lig4<tm1Icrf>,Mre11a<tm1Jpt>/Mre11a<tm1Jpt>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mre11a<tm1Jpt>|Lig4<tm1Icrf>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cellular sensitivity to ionizing radiation
  http://purl.obolibrary.org/obo/MP_0004228

文献

http://purl.org/net/cito/citesAsAuthority

• Erin R P. Shull, et.al., Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS., Genes & development, 2009, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/19171781