increased response of heart to induced stress_Raf1<tm1.1Bgn>/Raf1<+>

http://metadb.riken.jp/0004485I129S6SvEvTacC57BL6NCrRaf1tm11BgnRaf1Raf1tm11BgnRaf1

increased response of heart to induced stress_Raf1<tm1.1Bgn>/Raf1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• v-raf-leukemia viral oncogene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97847

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Raf1<tm1.1Bgn>/Raf1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Raf1<tm1.1Bgn>|Raf1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6NCr

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased response of heart to induced stress
  http://purl.obolibrary.org/obo/MP_0004485

文献

http://purl.org/net/cito/citesAsAuthority

• Xue. Wu, et.al., MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1(L613V) mutation., The Journal of clinical investigation, 2011, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/21339642