increased incidence of tumors by chemical induction_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Stat3<tm1Vpo>/Stat3<tm1Vpo>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0004499I129P2OlaHsd129S1Sv129X1SvJC57BL6DBAPtpn11tm1GsfPtpn11tm1GsfStat3tm1VpoStat3tm1VpoTgAlbcre21Mgn0Stat3tm1VpoTgAlbcre21MgnPtpn11tm1Gsf

increased incidence of tumors by chemical induction_Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Stat3<tm1Vpo>/Stat3<tm1Vpo>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein tyrosine phosphatase, non-receptor type 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:99511
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• signal transducer and activator of transcription 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:103038

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptpn11<tm1Gsf>/Ptpn11<tm1Gsf>,Stat3<tm1Vpo>/Stat3<tm1Vpo>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Stat3<tm1Vpo>|Tg(Alb-cre)21Mgn|Ptpn11<tm1Gsf>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased incidence of tumors by chemical induction
  http://purl.obolibrary.org/obo/MP_0004499

文献

http://purl.org/net/cito/citesAsAuthority

• Emilie A. Bard-Chapeau, et.al., Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis., Cancer cell, 2011, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/21575863