decreased incidence of tumors by chemical induction_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/?

http://metadb.riken.jp/0004502I129Sv129P2OlaHsdC57BL6FVBICRKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1DerTrp53tm1BrnKrastm4TyjKrasTgKRT5crePGR1Der

decreased incidence of tumors by chemical induction_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• transgene insertion 1, Dennis R Roop
  http://metadb.riken.jp/db/mgi_rdf/MGI:2651407
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brn>|Kras<tm4Tyj>|Kras<+>|Tg(KRT5-cre/PGR)1Der

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * FVB * ICR

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased incidence of tumors by chemical induction
  http://purl.obolibrary.org/obo/MP_0004502

文献

http://purl.org/net/cito/citesAsAuthority

• Carlos. Caulin, et.al., An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations., The Journal of clinical investigation, 2007, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/17607363