abnormal thyroid follicular cell morphology_Pten<tm1.1Mwst>/Pten<tm1.1Mwst>,Tg(TPO-cre)1Shk/0

http://metadb.riken.jp/0004697I129FVBNCrPtentm11MwstPtentm11MwstTgTPOcre1Shk0TgTPOcre1ShkPtentm11Mwst

abnormal thyroid follicular cell morphology_Pten<tm1.1Mwst>/Pten<tm1.1Mwst>,Tg(TPO-cre)1Shk/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion 1, Shioko Kimura
  http://metadb.riken.jp/db/mgi_rdf/MGI:3653643

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1.1Mwst>/Pten<tm1.1Mwst>,Tg(TPO-cre)1Shk/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TPO-cre)1Shk|Pten<tm1.1Mwst>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * FVB/NCr

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal thyroid follicular cell morphology
  http://purl.obolibrary.org/obo/MP_0004697

文献

http://purl.org/net/cito/citesAsAuthority

• Daphne R. Pringle, et.al., Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice., The Journal of clinical endocrinology and metabolism, 2014, 99
  http://rdf.ncbi.nlm.nih.gov/pubmed/24512487