abnormal loop of Henle morphology_Ttc21b<tm2c(KOMP)Wtsi>/Ttc21b<aln>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0004755I129S1Sv129X1SvJC57BL6NTtc21btm2cKOMPWtsiTtc21balnGtROSA26Sortm1creERTNatGtROSA26SorTtc21btm2cKOMPWtsiTtc21balnGtROSA26SorGtROSA26Sortm1creERTNat

abnormal loop of Henle morphology_Ttc21b<tm2c(KOMP)Wtsi>/Ttc21b<aln>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• tetratricopeptide repeat domain 21B
  http://metadb.riken.jp/db/mgi_rdf/MGI:1920918

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ttc21b<tm2c(KOMP)Wtsi>/Ttc21b<aln>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ttc21b<tm2c(KOMP)Wtsi>|Ttc21b<aln>|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1(cre/ERT)Nat>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal loop of Henle morphology
  http://purl.obolibrary.org/obo/MP_0004755

文献

http://purl.org/net/cito/citesAsAuthority

• Pamela V. Tran, et.al., Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models., Journal of the American Society of Nephrology : JASN, 2014, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/24700869