increased bile salt level_Abcb4<tm1Bor>/Abcb4<tm1Bor>,Por<tm1Wolf>/Por<tm1Wolf>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0004789I129P2OlaHsdC57BL6DBAFVBNAbcb4tm1BorAbcb4tm1BorPortm1WolfPortm1WolfTgAlbcre21Mgn0Portm1WolfTgAlbcre21MgnAbcb4tm1Bor

increased bile salt level_Abcb4<tm1Bor>/Abcb4<tm1Bor>,Por<tm1Wolf>/Por<tm1Wolf>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• P450 (cytochrome) oxidoreductase
  http://metadb.riken.jp/db/mgi_rdf/MGI:97744
• ATP-binding cassette, sub-family B (MDR/TAP), member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:97569
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Abcb4<tm1Bor>/Abcb4<tm1Bor>,Por<tm1Wolf>/Por<tm1Wolf>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Por<tm1Wolf>|Tg(Alb-cre)21Mgn|Abcb4<tm1Bor>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased bile salt level
  http://purl.obolibrary.org/obo/MP_0004789

文献

http://purl.org/net/cito/citesAsAuthority

• Cindy. Kunne, et.al., Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis., Laboratory investigation; a journal of technical methods and pathology, 2014, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/25068656