increased susceptibility to experimental autoimmune encephalomyelitis_Mog<tm1Dpd>/Mog<tm1Dpd>,Rag2<tm1Cgn>/Rag2<tm1Cgn>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0

http://metadb.riken.jp/0004799I129S2SvPasC57BL6Mogtm1DpdMogtm1DpdRag2tm1CgnRag2tm1CgnTgTcra2D2Tcrb2D21Kuch0Mogtm1DpdTgTcra2D2Tcrb2D21KuchRag2tm1Cgn

increased susceptibility to experimental autoimmune encephalomyelitis_Mog<tm1Dpd>/Mog<tm1Dpd>,Rag2<tm1Cgn>/Rag2<tm1Cgn>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• recombination activating gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97849
• transgene insertion 1, Vijay Kuchroo
  http://metadb.riken.jp/db/mgi_rdf/MGI:3700835
• myelin oligodendrocyte glycoprotein
  http://metadb.riken.jp/db/mgi_rdf/MGI:97435

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mog<tm1Dpd>/Mog<tm1Dpd>,Rag2<tm1Cgn>/Rag2<tm1Cgn>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mog<tm1Dpd>|Tg(Tcra2D2,Tcrb2D2)1Kuch|Rag2<tm1Cgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to experimental autoimmune encephalomyelitis
  http://purl.obolibrary.org/obo/MP_0004799

文献

http://purl.org/net/cito/citesAsAuthority

• Gurumoorthy. Krishnamoorthy, et.al., Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis., Nature medicine, 2009, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19483694