Gurumoorthy. Krishnamoorthy, et.al., Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis., Nature medicine, 2009, 15

http://rdf.ncbi.nlm.nih.gov/pubmed/19483694

Gurumoorthy. Krishnamoorthy, et.al., Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis., Nature medicine, 2009, 15

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal optic nerve morphology_Igh-J<tm1Aigl>/Igh-J<+>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0001330I129S1Sv129X1SvJC57BL6IghJtm1AiglIghJTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchIghJtm1AiglIghJ
• abnormal optic nerve morphology_Igh-J<tm1Aigl>/Igh-J<+>,Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0001330I129S1Sv129S2SvPas129X1SvJC57BL6IghJtm1AiglIghJMogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0IghJtm1AiglTgTcra2D2Tcrb2D21KuchIghJMogtm1Dpd
• increased susceptibility to experimental autoimmune encephalomyelitis_Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0004799I129S2SvPasC57BL6Mogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0Mogtm1DpdTgTcra2D2Tcrb2D21Kuch
• demyelination_Igh-J<tm1Aigl>/Igh-J<+>,Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0000921I129S1Sv129S2SvPas129X1SvJC57BL6IghJtm1AiglIghJMogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0IghJtm1AiglTgTcra2D2Tcrb2D21KuchIghJMogtm1Dpd
• abnormal spinal cord morphology_Igh-J<tm1Aigl>/Igh-J<+>,Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0000955I129S1Sv129S2SvPas129X1SvJC57BL6IghJtm1AiglIghJMogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0IghJtm1AiglTgTcra2D2Tcrb2D21KuchIghJMogtm1Dpd
• abnormal spinal cord morphology_Igh-J<tm1Aigl>/Igh-J<+>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0000955I129S1Sv129X1SvJC57BL6IghJtm1AiglIghJTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchIghJtm1AiglIghJ
• demyelination_Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0000921I129S2SvPasC57BL6Mogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0Mogtm1DpdTgTcra2D2Tcrb2D21Kuch
• abnormal optic nerve morphology_Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0001330I129S2SvPasC57BL6Mogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0Mogtm1DpdTgTcra2D2Tcrb2D21Kuch
• CNS inflammation_Igh-J<tm1Aigl>/Igh-J<+>,Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0006082I129S1Sv129S2SvPas129X1SvJC57BL6IghJtm1AiglIghJMogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0IghJtm1AiglTgTcra2D2Tcrb2D21KuchIghJMogtm1Dpd
• paralysis_Igh-J<tm1Aigl>/Igh-J<+>,Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0000753I129S1Sv129S2SvPas129X1SvJC57BL6IghJtm1AiglIghJMogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0IghJtm1AiglTgTcra2D2Tcrb2D21KuchIghJMogtm1Dpd
• abnormal nervous system morphology_Igh-J<tm1Aigl>/Igh-J<+>,Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0003632I129S1Sv129S2SvPas129X1SvJC57BL6IghJtm1AiglIghJMogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0IghJtm1AiglTgTcra2D2Tcrb2D21KuchIghJMogtm1Dpd
• CNS inflammation_Igh-J<tm1Aigl>/Igh-J<+>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0006082I129S1Sv129X1SvJC57BL6IghJtm1AiglIghJTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchIghJtm1AiglIghJ
• muscle hypertonia_Igh-J<tm1Aigl>/Igh-J<+>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0004143I129S1Sv129X1SvJC57BL6IghJtm1AiglIghJTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchIghJtm1AiglIghJ
• muscle hypertonia_Igh-J<tm1Aigl>/Igh-J<+>,Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0004143I129S1Sv129S2SvPas129X1SvJC57BL6IghJtm1AiglIghJMogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0IghJtm1AiglTgTcra2D2Tcrb2D21KuchIghJMogtm1Dpd
• increased susceptibility to experimental autoimmune encephalomyelitis_Mog<tm1Dpd>/Mog<tm1Dpd>,Rag2<tm1Cgn>/Rag2<tm1Cgn>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0004799I129S2SvPasC57BL6Mogtm1DpdMogtm1DpdRag2tm1CgnRag2tm1CgnTgTcra2D2Tcrb2D21Kuch0Mogtm1DpdTgTcra2D2Tcrb2D21KuchRag2tm1Cgn
• abnormal spinal cord morphology_Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0000955I129S2SvPasC57BL6Mogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0Mogtm1DpdTgTcra2D2Tcrb2D21Kuch
• CNS inflammation_Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0006082I129S2SvPasC57BL6Mogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0Mogtm1DpdTgTcra2D2Tcrb2D21Kuch
• abnormal nervous system morphology_Igh-J<tm1Aigl>/Igh-J<+>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0003632I129S1Sv129X1SvJC57BL6IghJtm1AiglIghJTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchIghJtm1AiglIghJ
• muscle hypertonia_Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0004143I129S2SvPasC57BL6Mogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0Mogtm1DpdTgTcra2D2Tcrb2D21Kuch
• paralysis_Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0000753I129S2SvPasC57BL6Mogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0Mogtm1DpdTgTcra2D2Tcrb2D21Kuch
• increased susceptibility to experimental autoimmune encephalomyelitis_Igh-J<tm1Aigl>/Igh-J<+>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0004799I129S1Sv129X1SvJC57BL6IghJtm1AiglIghJTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchIghJtm1AiglIghJ
• abnormal nervous system morphology_Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0003632I129S2SvPasC57BL6Mogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0Mogtm1DpdTgTcra2D2Tcrb2D21Kuch
• increased susceptibility to experimental autoimmune encephalomyelitis_Mog<tm1(cre)Gkl>/Mog<tm1(cre)Gkl>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0004799C57BL6Mogtm1creGklTgTcra2D2Tcrb2D21KuchMogtm1creGklMogtm1creGklTgTcra2D2Tcrb2D21Kuch0Mogtm1creGklTgTcra2D2Tcrb2D21Kuch
• increased susceptibility to experimental autoimmune encephalomyelitis_Igh-J<tm1Aigl>/Igh-J<+>,Mog<tm1Dpd>/Mog<tm1Dpd>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0004799I129S1Sv129S2SvPas129X1SvJC57BL6IghJtm1AiglIghJMogtm1DpdMogtm1DpdTgTcra2D2Tcrb2D21Kuch0IghJtm1AiglTgTcra2D2Tcrb2D21KuchIghJMogtm1Dpd
• demyelination_Igh-J<tm1Aigl>/Igh-J<+>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0000921I129S1Sv129X1SvJC57BL6IghJtm1AiglIghJTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchIghJtm1AiglIghJ
• paralysis_Igh-J<tm1Aigl>/Igh-J<+>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0
  http://metadb.riken.jp/0000753I129S1Sv129X1SvJC57BL6IghJtm1AiglIghJTgTcra2D2Tcrb2D21Kuch0TgTcra2D2Tcrb2D21KuchIghJtm1AiglIghJ