increased susceptibility to autoimmune diabetes_Tg(Ins2-CD86)12B70Flv/0,Tg(Ins2-Tnf)17Flv/0

http://metadb.riken.jp/0004803IC57BL6CBACaTgIns2CD8612B70Flv0TgIns2Tnf17Flv0TgIns2CD8612B70FlvTgIns2Tnf17Flv

increased susceptibility to autoimmune diabetes_Tg(Ins2-CD86)12B70Flv/0,Tg(Ins2-Tnf)17Flv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 17, Richard Flavell
  http://metadb.riken.jp/db/mgi_rdf/MGI:3764662
• transgene insertion 12B70, Richard Flavell
  http://metadb.riken.jp/db/mgi_rdf/MGI:3764557

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Ins2-CD86)12B70Flv/0,Tg(Ins2-Tnf)17Flv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-CD86)12B70Flv|Tg(Ins2-Tnf)17Flv

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA/Ca

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to autoimmune diabetes
  http://purl.obolibrary.org/obo/MP_0004803

文献

http://purl.org/net/cito/citesAsAuthority

• S. Guerder, et.al., Autoimmunity without diabetes in transgenic mice expressing beta cell-specific CD86, but not CD80: parameters that trigger progression to diabetes., Journal of immunology (Baltimore, Md. : 1950), 1998, 161
  http://rdf.ncbi.nlm.nih.gov/pubmed/9725204