increased hematopoietic stem cell number_Trp53<tm1Tyj>/Trp53<tm1.1Umol>

http://metadb.riken.jp/0004809I129S2SvPas129S6SvEvTacC57BL6C57BL6NTacTrp53tm1TyjTrp53tm11UmolTrp53tm1TyjTrp53tm11Umol

increased hematopoietic stem cell number_Trp53<tm1Tyj>/Trp53<tm1.1Umol>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Tyj>/Trp53<tm1.1Umol>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Tyj>|Trp53<tm1.1Umol>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004809

文献

http://purl.org/net/cito/citesAsAuthority

• W. Hanel, et.al., Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis., Cell death and differentiation, 2013, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/23538418