increased hematopoietic stem cell number_Nr4a1<tm1Jmi>/Nr4a1<tm1Jmi>,Nr4a3<tm1Omc>/Nr4a3<tm1Omc>

http://metadb.riken.jp/0004809I129SSvEv129S2SvPasC57BL6Nr4a1tm1JmiNr4a1tm1JmiNr4a3tm1OmcNr4a3tm1OmcNr4a3tm1OmcNr4a1tm1Jmi

increased hematopoietic stem cell number_Nr4a1<tm1Jmi>/Nr4a1<tm1Jmi>,Nr4a3<tm1Omc>/Nr4a3<tm1Omc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• nuclear receptor subfamily 4, group A, member 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1352457
• nuclear receptor subfamily 4, group A, member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1352454

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nr4a1<tm1Jmi>/Nr4a1<tm1Jmi>,Nr4a3<tm1Omc>/Nr4a3<tm1Omc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nr4a3<tm1Omc>|Nr4a1<tm1Jmi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004809

文献

http://purl.org/net/cito/citesAsAuthority

• Shannon E. Mullican, et.al., Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia., Nature medicine, 2007, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/17515897