increased hematopoietic stem cell number_Tet2<tm1.1Iaai>/Tet2<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0004809I129SSvEvC57BL6CBATet2tm11IaaiTet2tm11IaaiTgMx1cre1Cgn0TgMx1cre1CgnTet2tm11Iaai

increased hematopoietic stem cell number_Tet2<tm1.1Iaai>/Tet2<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• tet methylcytosine dioxygenase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2443298

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tet2<tm1.1Iaai>/Tet2<tm1.1Iaai>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Tet2<tm1.1Iaai>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004809

文献

http://purl.org/net/cito/citesAsAuthority

• Esther A. Obeng, et.al., Physiologic Expression of Sf3b1(K700E) Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation., Cancer cell, 2016, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/27622333