decreased hematopoietic stem cell number_Kdm1a<tm1.1Sho>/Kdm1a<tm1.1Sho>,Tg(Vav1-icre)A2Kio/0

http://metadb.riken.jp/0004810I129C57BL6C57BL10CBACaKdm1atm11ShoKdm1atm11ShoTgVav1icreA2Kio0TgVav1icreA2KioKdm1atm11Sho

decreased hematopoietic stem cell number_Kdm1a<tm1.1Sho>/Kdm1a<tm1.1Sho>,Tg(Vav1-icre)A2Kio/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lysine (K)-specific demethylase 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1196256
• transgene insertion A2, Dimitris Kioussis
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449945

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kdm1a<tm1.1Sho>/Kdm1a<tm1.1Sho>,Tg(Vav1-icre)A2Kio/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vav1-icre)A2Kio|Kdm1a<tm1.1Sho>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004810

文献

http://purl.org/net/cito/citesAsAuthority

• Marc A. Kerenyi, et.al., Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation., eLife, 2013, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/23795291