decreased hematopoietic stem cell number_Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>

http://metadb.riken.jp/0004810I129S1Sv129X1SvJCD1ICRCdk4tm1BbdCdk4tm1BbdCdk6tm1BbdCdk6tm1BbdCdk4tm1BbdCdk6tm1Bbd

decreased hematopoietic stem cell number_Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1277162
• cyclin-dependent kinase 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88357

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdk4<tm1Bbd>|Cdk6<tm1Bbd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * CD-1 * ICR

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004810

文献

http://purl.org/net/cito/citesAsAuthority

• Marcos. Malumbres, et.al., Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6., Cell, 2004, 118
  http://rdf.ncbi.nlm.nih.gov/pubmed/15315761