Marcos. Malumbres, et.al., Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6., Cell, 2004, 118

http://rdf.ncbi.nlm.nih.gov/pubmed/15315761

Marcos. Malumbres, et.al., Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6., Cell, 2004, 118

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cdk6<tm1Bbd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053975

class

http://purl.org/net/cito/citesAsAuthority

• Cdk6<tm1Bbd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053975

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased leukocyte cell number_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0000221I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• extramedullary hematopoiesis_Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0000240I129S1Sv129X1SvJCD1ICRCdk4tm1BbdCdk4tm1BbdCdk6tm1BbdCdk6tm1BbdCdk4tm1BbdCdk6tm1Bbd
• liver hypoplasia_Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0000600I129S1Sv129X1SvJCD1ICRCdk4tm1BbdCdk4tm1BbdCdk6tm1BbdCdk6tm1BbdCdk4tm1BbdCdk6tm1Bbd
• abnormal spleen morphology_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0000689I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• small spleen_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0000692I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• spleen hypoplasia_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0000694I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
他26件を見る
• abnormal thymus morphology_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0000703I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• abnormal spermatogenesis_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0001156I129S1Sv129X1SvJCD1Cdk2tm1SgoCdk2tm1SgoCdk6tm1BbdCdk6tm1BbdCdk6tm1BbdCdk2tm1Sgo
• decreased body weight_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• decreased embryo size_Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0001698I129S1Sv129X1SvJCD1ICRCdk4tm1BbdCdk4tm1BbdCdk6tm1BbdCdk6tm1BbdCdk4tm1BbdCdk6tm1Bbd
• thymus hypoplasia_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0001823I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• reduced female fertility_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0001923I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• infertility_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0001924I129S1Sv129X1SvJCD1Cdk2tm1SgoCdk2tm1SgoCdk6tm1BbdCdk6tm1BbdCdk6tm1BbdCdk2tm1Sgo
• abnormal gametogenesis_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0001929I129S1Sv129X1SvJCD1Cdk2tm1SgoCdk2tm1SgoCdk6tm1BbdCdk6tm1BbdCdk6tm1BbdCdk2tm1Sgo
• abnormal oogenesis_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0001931I129S1Sv129X1SvJCD1Cdk2tm1SgoCdk2tm1SgoCdk6tm1BbdCdk6tm1BbdCdk6tm1BbdCdk2tm1Sgo
• abnormal definitive hematopoiesis_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0002123I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• abnormal spleen red pulp morphology_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0002356I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• abnormal hematopoietic system morphology/development_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0002396I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• abnormal erythrocyte morphology_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0002447I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• abnormal erythrocyte morphology_Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0002447I129S1Sv129X1SvJCD1ICRCdk4tm1BbdCdk4tm1BbdCdk6tm1BbdCdk6tm1BbdCdk4tm1BbdCdk6tm1Bbd
• increased mean corpuscular volume_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0002590I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• decreased mature ovarian follicle number_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0002682I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• decreased erythrocyte cell number_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0002875I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• decreased erythrocyte cell number_Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0002875I129S1Sv129X1SvJCD1ICRCdk4tm1BbdCdk4tm1BbdCdk6tm1BbdCdk6tm1BbdCdk4tm1BbdCdk6tm1Bbd
• decreased hematopoietic stem cell number_Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0004810I129S1Sv129X1SvJCD1ICRCdk4tm1BbdCdk4tm1BbdCdk6tm1BbdCdk6tm1BbdCdk4tm1BbdCdk6tm1Bbd
• decreased T cell proliferation_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0005095I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• increased mean corpuscular hemoglobin concentration_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0005641I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• increased single-positive T cell number_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0008082I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• decreased megakaryocyte cell number_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0008255I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd
• neonatal lethality, complete penetrance_Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0011087I129S1Sv129X1SvJCD1ICRCdk4tm1BbdCdk4tm1BbdCdk6tm1BbdCdk6tm1BbdCdk4tm1BbdCdk6tm1Bbd
• lethality throughout fetal growth and development, incomplete penetrance_Cdk4<tm1Bbd>/Cdk4<tm1Bbd>,Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0011109I129S1Sv129X1SvJCD1ICRCdk4tm1BbdCdk4tm1BbdCdk6tm1BbdCdk6tm1BbdCdk4tm1BbdCdk6tm1Bbd
• thymus cortex atrophy_Cdk6<tm1Bbd>/Cdk6<tm1Bbd>
  http://metadb.riken.jp/0013585I129S1Sv129X1SvJCD1Cdk6tm1BbdCdk6tm1BbdCdk6tm1Bbd