decreased hematopoietic stem cell number_Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0004810I129S2SvPasC57BL6CBASJLKmt2atm11ErnsKmt2atm11ErnsTgMx1cre1Cgn0Kmt2atm11ErnsTgMx1cre1Cgn

decreased hematopoietic stem cell number_Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lysine (K)-specific methyltransferase 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:96995
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kmt2a<tm1.1Erns>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004810

文献

http://purl.org/net/cito/citesAsAuthority

• Craig D. Jude, et.al., Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors., Cell stem cell, 2007, 1
  http://rdf.ncbi.nlm.nih.gov/pubmed/18371366