decreased hematopoietic stem cell number_Pml<tm1(PML/RARA)Ley>/Pml<+>,Tg(CAG-cre/Esr1*)5Amc/0

http://metadb.riken.jp/0004810IBALBcJC57BL6CBAPmltm1PMLRARALeyPmlTgCAGcreEsr15Amc0TgCAGcreEsr15AmcPmltm1PMLRARALeyPml

decreased hematopoietic stem cell number_Pml<tm1(PML/RARA)Ley>/Pml<+>,Tg(CAG-cre/Esr1*)5Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765
• promyelocytic leukemia
  http://metadb.riken.jp/db/mgi_rdf/MGI:104662

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pml<tm1(PML/RARA)Ley>/Pml<+>,Tg(CAG-cre/Esr1*)5Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CAG-cre/Esr1*)5Amc|Pml<tm1(PML/RARA)Ley>|Pml<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/cJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004810

文献

http://purl.org/net/cito/citesAsAuthority

• John S. Welch, et.al., PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice., The Journal of clinical investigation, 2011, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/21364283