decreased hematopoietic stem cell number_Prkaa1<tm1.1Sjm>/Prkaa1<tm1.1Sjm>,Prkaa2<tm1.1Sjm>/Prkaa2<tm1.1Sjm>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0004810IC57BL6CBASJLPrkaa1tm11SjmPrkaa1tm11SjmPrkaa2tm11SjmPrkaa2tm11SjmTgMx1cre1Cgn0Prkaa1tm11SjmPrkaa2tm11SjmTgMx1cre1Cgn

decreased hematopoietic stem cell number_Prkaa1<tm1.1Sjm>/Prkaa1<tm1.1Sjm>,Prkaa2<tm1.1Sjm>/Prkaa2<tm1.1Sjm>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein kinase, AMP-activated, alpha 1 catalytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:2145955
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• protein kinase, AMP-activated, alpha 2 catalytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:1336173

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prkaa1<tm1.1Sjm>/Prkaa1<tm1.1Sjm>,Prkaa2<tm1.1Sjm>/Prkaa2<tm1.1Sjm>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Prkaa1<tm1.1Sjm>|Prkaa2<tm1.1Sjm>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004810

文献

http://purl.org/net/cito/citesAsAuthority

• Daisuke. Nakada, et.al., Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells., Nature, 2010, 468
  http://rdf.ncbi.nlm.nih.gov/pubmed/21124450