abnormal class switch recombination_Igh<tm2Cgn>/Igh<tm2Cgn>,Igk<tm1Rsky>/Igk<tm1Rsky>,Lig4<tm1Fwa>/Lig4<tm1Fwa>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

http://metadb.riken.jp/0004816I129P2OlaHsd129S2SvPas129S6SvEvTacIghtm2CgnIghtm2CgnIgktm1RskyIgktm1RskyLig4tm1FwaLig4tm1FwaTrp53tm1TyjTrp53tm1TyjIgktm1RskyLig4tm1FwaTrp53tm1TyjIghtm2Cgn

abnormal class switch recombination_Igh<tm2Cgn>/Igh<tm2Cgn>,Igk<tm1Rsky>/Igk<tm1Rsky>,Lig4<tm1Fwa>/Lig4<tm1Fwa>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin kappa chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96494
• ligase IV, DNA, ATP-dependent
  http://metadb.riken.jp/db/mgi_rdf/MGI:1335098
• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh<tm2Cgn>/Igh<tm2Cgn>,Igk<tm1Rsky>/Igk<tm1Rsky>,Lig4<tm1Fwa>/Lig4<tm1Fwa>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igk<tm1Rsky>|Lig4<tm1Fwa>|Trp53<tm1Tyj>|Igh<tm2Cgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal class switch recombination
  http://purl.obolibrary.org/obo/MP_0004816

文献

http://purl.org/net/cito/citesAsAuthority

• Catherine T. Yan, et.al., IgH class switching and translocations use a robust non-classical end-joining pathway., Nature, 2007, 449
  http://rdf.ncbi.nlm.nih.gov/pubmed/17713479