Catherine T. Yan, et.al., IgH class switching and translocations use a robust non-classical end-joining pathway., Nature, 2007, 449

http://rdf.ncbi.nlm.nih.gov/pubmed/17713479

Catherine T. Yan, et.al., IgH class switching and translocations use a robust non-classical end-joining pathway., Nature, 2007, 449

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal class switch recombination_Lig4<tm1Fwa>/Lig4<tm1Fwa>,Tg(Cr2-cre)3Cgn/0,Xrcc4<tm2Fwa>/Xrcc4<tm2Fwa>
  http://metadb.riken.jp/0004816I129S6SvEvTacLig4tm1FwaLig4tm1FwaTgCr2cre3Cgn0Xrcc4tm2FwaXrcc4tm2FwaXrcc4tm2FwaTgCr2cre3CgnLig4tm1Fwa
• spontaneous chromosome breakage_Lig4<tm1Fwa>/Lig4<tm1Fwa>,Tg(Cr2-cre)3Cgn/0,Xrcc4<tm2Fwa>/Xrcc4<tm2Fwa>
  http://metadb.riken.jp/0004029I129S6SvEvTacLig4tm1FwaLig4tm1FwaTgCr2cre3Cgn0Xrcc4tm2FwaXrcc4tm2FwaXrcc4tm2FwaTgCr2cre3CgnLig4tm1Fwa
• increased cellular sensitivity to ionizing radiation_Igh<tm2Cgn>/Igh<tm2Cgn>,Igk<tm1Rsky>/Igk<tm1Rsky>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc4<tm1Fwa>/Xrcc4<tm1Fwa>
  http://metadb.riken.jp/0004227I129P2OlaHsd129S2SvPas129S6SvEvTacIghtm2CgnIghtm2CgnIgktm1RskyIgktm1RskyTrp53tm1TyjTrp53tm1TyjXrcc4tm1FwaXrcc4tm1FwaIghtm2CgnTrp53tm1TyjIgktm1RskyXrcc4tm1Fwa
• spontaneous chromosome breakage_Igh<tm2Cgn>/Igh<tm2Cgn>,Igk<tm1Rsky>/Igk<tm1Rsky>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc4<tm1Fwa>/Xrcc4<tm1Fwa>
  http://metadb.riken.jp/0004029I129P2OlaHsd129S2SvPas129S6SvEvTacIghtm2CgnIghtm2CgnIgktm1RskyIgktm1RskyTrp53tm1TyjTrp53tm1TyjXrcc4tm1FwaXrcc4tm1FwaIghtm2CgnTrp53tm1TyjIgktm1RskyXrcc4tm1Fwa
• abnormal class switch recombination_Igh<tm2Cgn>/Igh<tm2Cgn>,Igk<tm1Rsky>/Igk<tm1Rsky>,Lig4<tm1Fwa>/Lig4<tm1Fwa>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0004816I129P2OlaHsd129S2SvPas129S6SvEvTacIghtm2CgnIghtm2CgnIgktm1RskyIgktm1RskyLig4tm1FwaLig4tm1FwaTrp53tm1TyjTrp53tm1TyjIgktm1RskyLig4tm1FwaTrp53tm1TyjIghtm2Cgn
• increased cellular sensitivity to ionizing radiation_Lig4<tm1Fwa>/Lig4<tm1Fwa>,Tg(Cr2-cre)3Cgn/0,Xrcc4<tm2Fwa>/Xrcc4<tm2Fwa>
  http://metadb.riken.jp/0004227I129S6SvEvTacLig4tm1FwaLig4tm1FwaTgCr2cre3Cgn0Xrcc4tm2FwaXrcc4tm2FwaXrcc4tm2FwaTgCr2cre3CgnLig4tm1Fwa
• abnormal class switch recombination_Igh<tm2Cgn>/Igh<tm2Cgn>,Igk<tm1Rsky>/Igk<tm1Rsky>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc4<tm1Fwa>/Xrcc4<tm1Fwa>
  http://metadb.riken.jp/0004816I129P2OlaHsd129S2SvPas129S6SvEvTacIghtm2CgnIghtm2CgnIgktm1RskyIgktm1RskyTrp53tm1TyjTrp53tm1TyjXrcc4tm1FwaXrcc4tm1FwaIghtm2CgnTrp53tm1TyjIgktm1RskyXrcc4tm1Fwa