abnormal small intestine crypts of Lieberkuhn morphology_Rnf43<tm1Cle>/Rnf43<tm1Cle>,Znrf3<tm1Cle>/Znrf3<tm1Cle>,Tg(Vil-cre/ERT2)23Syr/0

http://metadb.riken.jp/0004841IC57BL6DBA2Rnf43tm1CleRnf43tm1CleZnrf3tm1CleZnrf3tm1CleTgVilcreERT223Syr0TgVilcreERT223SyrRnf43tm1CleZnrf3tm1Cle

abnormal small intestine crypts of Lieberkuhn morphology_Rnf43<tm1Cle>/Rnf43<tm1Cle>,Znrf3<tm1Cle>/Znrf3<tm1Cle>,Tg(Vil-cre/ERT2)23Syr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• zinc and ring finger 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:3039616
• transgene insertion 23, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053810
• ring finger protein 43
  http://metadb.riken.jp/db/mgi_rdf/MGI:2442609

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rnf43<tm1Cle>/Rnf43<tm1Cle>,Znrf3<tm1Cle>/Znrf3<tm1Cle>,Tg(Vil-cre/ERT2)23Syr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil-cre/ERT2)23Syr|Rnf43<tm1Cle>|Znrf3<tm1Cle>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal small intestine crypts of Lieberkuhn morphology
  http://purl.obolibrary.org/obo/MP_0004841

文献

http://purl.org/net/cito/citesAsAuthority

• Bon-Kyoung. Koo, et.al., Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors., Nature, 2012, 488
  http://rdf.ncbi.nlm.nih.gov/pubmed/22895187