Bon-Kyoung. Koo, et.al., Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors., Nature, 2012, 488

http://rdf.ncbi.nlm.nih.gov/pubmed/22895187

Bon-Kyoung. Koo, et.al., Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors., Nature, 2012, 488

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Znrf3<tm1Cle>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5439366
• Rnf43<tm1Cle>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5439364

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased Paneth cell number_Rnf43<tm1Cle>/Rnf43<tm1Cle>,Znrf3<tm1Cle>/Znrf3<tm1Cle>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0013485IC57BL6DBA2Rnf43tm1CleRnf43tm1CleZnrf3tm1CleZnrf3tm1CleTgVilcreERT223Syr0TgVilcreERT223SyrRnf43tm1CleZnrf3tm1Cle
• abnormal small intestinal crypt cell proliferation_Rnf43<tm1Cle>/Rnf43<tm1Cle>,Znrf3<tm1Cle>/Znrf3<tm1Cle>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0010157IC57BL6DBA2Rnf43tm1CleRnf43tm1CleZnrf3tm1CleZnrf3tm1CleTgVilcreERT223Syr0TgVilcreERT223SyrRnf43tm1CleZnrf3tm1Cle
• increased intestinal adenoma incidence_Rnf43<tm1Cle>/Rnf43<tm1Cle>,Znrf3<tm1Cle>/Znrf3<tm1Cle>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0002404IC57BL6DBA2Rnf43tm1CleRnf43tm1CleZnrf3tm1CleZnrf3tm1CleTgVilcreERT223Syr0TgVilcreERT223SyrRnf43tm1CleZnrf3tm1Cle
• increased intestinal adenoma incidence_Rnf43<tm1Cle>/Rnf43<tm1Cle>,Znrf3<tm1Cle>/Znrf3<tm1Cle>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>
  http://metadb.riken.jp/0002404I129P2OlaHsdRnf43tm1CleRnf43tm1CleZnrf3tm1CleZnrf3tm1CleLgr5tm1creERT2CleLgr5Lgr5Rnf43tm1CleLgr5tm1creERT2CleZnrf3tm1Cle
• abnormal small intestine crypts of Lieberkuhn morphology_Rnf43<tm1Cle>/Rnf43<tm1Cle>,Znrf3<tm1Cle>/Znrf3<tm1Cle>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0004841IC57BL6DBA2Rnf43tm1CleRnf43tm1CleZnrf3tm1CleZnrf3tm1CleTgVilcreERT223Syr0TgVilcreERT223SyrRnf43tm1CleZnrf3tm1Cle

class

http://purl.org/net/cito/citesAsAuthority

• Znrf3<tm1Cle>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5439366
• Rnf43<tm1Cle>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5439364