abnormal Paneth cell morphology_Cdc42<tm1Brak>/Cdc42<+>,Rab8a<tm1.1Aha>/Rab8a<+>,Tg(Vil1-cre)997Gum/0

http://metadb.riken.jp/0004843IC57BL6JSJLCdc42tm1BrakCdc42Rab8atm11AhaRab8aTgVil1cre997Gum0Rab8atm11AhaCdc42tm1BrakRab8aCdc42TgVil1cre997Gum

abnormal Paneth cell morphology_Cdc42<tm1Brak>/Cdc42<+>,Rab8a<tm1.1Aha>/Rab8a<+>,Tg(Vil1-cre)997Gum/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 997, Deborah L Gumucio
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446957
• RAB8A, member RAS oncogene family
  http://metadb.riken.jp/db/mgi_rdf/MGI:96960
• cell division cycle 42
  http://metadb.riken.jp/db/mgi_rdf/MGI:106211

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdc42<tm1Brak>/Cdc42<+>,Rab8a<tm1.1Aha>/Rab8a<+>,Tg(Vil1-cre)997Gum/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rab8a<tm1.1Aha>|Cdc42<tm1Brak>|Rab8a<+>|Cdc42<+>|Tg(Vil1-cre)997Gum

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal Paneth cell morphology
  http://purl.obolibrary.org/obo/MP_0004843

文献

http://purl.org/net/cito/citesAsAuthority

• Ryotaro. Sakamori, et.al., Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice., The Journal of clinical investigation, 2012, 122
  http://rdf.ncbi.nlm.nih.gov/pubmed/22354172