decreased energy expenditure_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>

http://metadb.riken.jp/0004890I129C57BL6JLeprtm11ChuaLeprtm11ChuaPrlhtm1creSmlnPrlhPrlhtm1creSmlnPrlhLeprtm11Chua

decreased energy expenditure_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• prolactin releasing hormone
  http://metadb.riken.jp/db/mgi_rdf/MGI:3644668
• leptin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104993

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Prlh<tm1(cre)Smln>|Prlh<+>|Lepr<tm1.1Chua>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased energy expenditure
  http://purl.obolibrary.org/obo/MP_0004890

文献

http://purl.org/net/cito/citesAsAuthority

• Garron T. Dodd, et.al., The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus., Cell metabolism, 2014, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/25176149