Garron T. Dodd, et.al., The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus., Cell metabolism, 2014, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/25176149

Garron T. Dodd, et.al., The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus., Cell metabolism, 2014, 20

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Prlh<tm1(cre)Smln>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5634277
• Prlh<tm2Smln>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5634278

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• obese_Prlh<tm2Smln>/Prlh<tm2Smln>
  http://metadb.riken.jp/0001261IC57BL6JPrlhtm2SmlnPrlhtm2SmlnPrlhtm2Smln
• decreased core body temperature_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>
  http://metadb.riken.jp/0011014I129C57BL6JLeprtm11ChuaLeprtm11ChuaPrlhtm1creSmlnPrlhPrlhtm1creSmlnPrlhLeprtm11Chua
• increased epididymal fat pad weight_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>
  http://metadb.riken.jp/0009288I129C57BL6JLeprtm11ChuaLeprtm11ChuaPrlhtm1creSmlnPrlhPrlhtm1creSmlnPrlhLeprtm11Chua
• increased body weight_Prlh<tm2Smln>/Prlh<tm2Smln>
  http://metadb.riken.jp/0001260IC57BL6JPrlhtm2SmlnPrlhtm2SmlnPrlhtm2Smln
• abnormal response/metabolism to endogenous compounds_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>
  http://metadb.riken.jp/0003638I129C57BL6JLeprtm11ChuaLeprtm11ChuaPrlhtm1creSmlnPrlhPrlhtm1creSmlnPrlhLeprtm11Chua
• abnormal body temperature homeostasis_Prlh<tm2Smln>/Prlh<tm2Smln>
  http://metadb.riken.jp/0001777IC57BL6JPrlhtm2SmlnPrlhtm2SmlnPrlhtm2Smln
• increased total body fat amount_Prlh<tm2Smln>/Prlh<tm2Smln>
  http://metadb.riken.jp/0010024IC57BL6JPrlhtm2SmlnPrlhtm2SmlnPrlhtm2Smln
• increased circulating leptin level_Prlh<tm2Smln>/Prlh<tm2Smln>
  http://metadb.riken.jp/0005669IC57BL6JPrlhtm2SmlnPrlhtm2SmlnPrlhtm2Smln
• obese_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>
  http://metadb.riken.jp/0001261I129C57BL6JLeprtm11ChuaLeprtm11ChuaPrlhtm1creSmlnPrlhPrlhtm1creSmlnPrlhLeprtm11Chua
• increased epididymal fat pad weight_Prlh<tm2Smln>/Prlh<tm2Smln>
  http://metadb.riken.jp/0009288IC57BL6JPrlhtm2SmlnPrlhtm2SmlnPrlhtm2Smln
• decreased core body temperature_Prlh<tm2Smln>/Prlh<tm2Smln>
  http://metadb.riken.jp/0011014IC57BL6JPrlhtm2SmlnPrlhtm2SmlnPrlhtm2Smln
• increased circulating insulin level_Prlh<tm2Smln>/Prlh<tm2Smln>
  http://metadb.riken.jp/0002079IC57BL6JPrlhtm2SmlnPrlhtm2SmlnPrlhtm2Smln
• increased food intake_Prlh<tm2Smln>/Prlh<tm2Smln>
  http://metadb.riken.jp/0011939IC57BL6JPrlhtm2SmlnPrlhtm2SmlnPrlhtm2Smln
• increased subcutaneous adipose tissue amount_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>
  http://metadb.riken.jp/0010934I129C57BL6JLeprtm11ChuaLeprtm11ChuaPrlhtm1creSmlnPrlhPrlhtm1creSmlnPrlhLeprtm11Chua
• decreased oxygen consumption_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>
  http://metadb.riken.jp/0005290I129C57BL6JLeprtm11ChuaLeprtm11ChuaPrlhtm1creSmlnPrlhPrlhtm1creSmlnPrlhLeprtm11Chua
• abnormal response/metabolism to endogenous compounds_Prlh<tm2Smln>/Prlh<tm2Smln>,Tg(Th-cre)1Tmd/0
  http://metadb.riken.jp/0003638IC57BL6C57BL6JSJLPrlhtm2SmlnPrlhtm2SmlnTgThcre1Tmd0Prlhtm2SmlnTgThcre1Tmd
• increased subcutaneous adipose tissue amount_Prlh<tm2Smln>/Prlh<tm2Smln>
  http://metadb.riken.jp/0010934IC57BL6JPrlhtm2SmlnPrlhtm2SmlnPrlhtm2Smln
• abnormal body temperature homeostasis_Prlh<tm2Smln>/Prlh<tm2Smln>,Tg(Th-cre)1Tmd/0
  http://metadb.riken.jp/0001777IC57BL6C57BL6JSJLPrlhtm2SmlnPrlhtm2SmlnTgThcre1Tmd0Prlhtm2SmlnTgThcre1Tmd
• increased susceptibility to diet-induced obesity_Prlh<tm2Smln>/Prlh<tm2Smln>
  http://metadb.riken.jp/0005658IC57BL6JPrlhtm2SmlnPrlhtm2SmlnPrlhtm2Smln
• increased circulating leptin level_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>
  http://metadb.riken.jp/0005669I129C57BL6JLeprtm11ChuaLeprtm11ChuaPrlhtm1creSmlnPrlhPrlhtm1creSmlnPrlhLeprtm11Chua
• abnormal body temperature homeostasis_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>
  http://metadb.riken.jp/0001777I129C57BL6JLeprtm11ChuaLeprtm11ChuaPrlhtm1creSmlnPrlhPrlhtm1creSmlnPrlhLeprtm11Chua
• hyperglycemia_Prlh<tm2Smln>/Prlh<tm2Smln>
  http://metadb.riken.jp/0001559IC57BL6JPrlhtm2SmlnPrlhtm2SmlnPrlhtm2Smln
• abnormal response/metabolism to endogenous compounds_Prlh<tm2Smln>/Prlh<tm2Smln>
  http://metadb.riken.jp/0003638IC57BL6JPrlhtm2SmlnPrlhtm2SmlnPrlhtm2Smln
• increased body weight_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>
  http://metadb.riken.jp/0001260I129C57BL6JLeprtm11ChuaLeprtm11ChuaPrlhtm1creSmlnPrlhPrlhtm1creSmlnPrlhLeprtm11Chua
• increased circulating insulin level_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>
  http://metadb.riken.jp/0002079I129C57BL6JLeprtm11ChuaLeprtm11ChuaPrlhtm1creSmlnPrlhPrlhtm1creSmlnPrlhLeprtm11Chua
• decreased energy expenditure_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Prlh<tm1(cre)Smln>/Prlh<+>
  http://metadb.riken.jp/0004890I129C57BL6JLeprtm11ChuaLeprtm11ChuaPrlhtm1creSmlnPrlhPrlhtm1creSmlnPrlhLeprtm11Chua

class

http://purl.org/net/cito/citesAsAuthority

• Prlh<tm1(cre)Smln>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5634277
• Prlh<tm2Smln>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5634278