decreased uterus weight_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Tg(Pomc-EGFP)1Low/0,Tg(Gnrh1-cre)1Dlc/0

http://metadb.riken.jp/0004905I129P2OlaHsdC57BL6C57BL6JCBAGtROSA26Sortm1DTARietGtROSA26SorTgPomcEGFP1Low0TgGnrh1cre1Dlc0GtROSA26Sortm1DTARietGtROSA26SorTgGnrh1cre1DlcTgPomcEGFP1Low

decreased uterus weight_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Tg(Pomc-EGFP)1Low/0,Tg(Gnrh1-cre)1Dlc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Malcolm J Low
  http://metadb.riken.jp/db/mgi_rdf/MGI:3776090
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Catherine Dulac
  http://metadb.riken.jp/db/mgi_rdf/MGI:3804662

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Tg(Pomc-EGFP)1Low/0,Tg(Gnrh1-cre)1Dlc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(DTA)Riet>|Gt(ROSA)26Sor<+>|Tg(Gnrh1-cre)1Dlc|Tg(Pomc-EGFP)1Low

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased uterus weight
  http://purl.obolibrary.org/obo/MP_0004905

文献

http://purl.org/net/cito/citesAsAuthority

• Thomas. Schmid, et.al., Loss of NSCL-2 in gonadotropin releasing hormone neurons leads to reduction of pro-opiomelanocortin neurons in specific hypothalamic nuclei and causes visceral obesity., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/23785158