Thomas. Schmid, et.al., Loss of NSCL-2 in gonadotropin releasing hormone neurons leads to reduction of pro-opiomelanocortin neurons in specific hypothalamic nuclei and causes visceral obesity., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, 33

http://rdf.ncbi.nlm.nih.gov/pubmed/23785158

Thomas. Schmid, et.al., Loss of NSCL-2 in gonadotropin releasing hormone neurons leads to reduction of pro-opiomelanocortin neurons in specific hypothalamic nuclei and causes visceral obesity., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, 33

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nhlh2<tm2Thbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5524018

class

http://purl.org/net/cito/citesAsAuthority

• Nhlh2<tm2Thbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5524018

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased white adipose tissue amount_Nhlh2<tm2Thbr>/Nhlh2<tm2Thbr>,Tg(Gnrh1-cre)1Dlc/0,Tg(Pomc-EGFP)1Low/0
  http://metadb.riken.jp/0000008I129S7SvEvBrdC57BL6C57BL6JCBANhlh2tm2ThbrNhlh2tm2ThbrTgGnrh1cre1Dlc0TgPomcEGFP1Low0Nhlh2tm2ThbrTgPomcEGFP1LowTgGnrh1cre1Dlc
• small ovary_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Tg(Pomc-EGFP)1Low/0,Tg(Gnrh1-cre)1Dlc/0
  http://metadb.riken.jp/0001127I129P2OlaHsdC57BL6C57BL6JCBAGtROSA26Sortm1DTARietGtROSA26SorTgPomcEGFP1Low0TgGnrh1cre1Dlc0GtROSA26Sortm1DTARietGtROSA26SorTgGnrh1cre1DlcTgPomcEGFP1Low
• increased body weight_Nhlh2<tm2Thbr>/Nhlh2<tm2Thbr>,Tg(CMV-cre)1Cgn/0
  http://metadb.riken.jp/0001260I129S7SvEvBrdBALBcJC57BL6Nhlh2tm2ThbrNhlh2tm2ThbrTgCMVcre1Cgn0Nhlh2tm2ThbrTgCMVcre1Cgn
• decreased uterus weight_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Tg(Pomc-EGFP)1Low/0,Tg(Gnrh1-cre)1Dlc/0
  http://metadb.riken.jp/0004905I129P2OlaHsdC57BL6C57BL6JCBAGtROSA26Sortm1DTARietGtROSA26SorTgPomcEGFP1Low0TgGnrh1cre1Dlc0GtROSA26Sortm1DTARietGtROSA26SorTgGnrh1cre1DlcTgPomcEGFP1Low
• decreased uterus weight_Nhlh2<tm2Thbr>/Nhlh2<tm2Thbr>,Tg(CMV-cre)1Cgn/0
  http://metadb.riken.jp/0004905I129S7SvEvBrdBALBcJC57BL6Nhlh2tm2ThbrNhlh2tm2ThbrTgCMVcre1Cgn0Nhlh2tm2ThbrTgCMVcre1Cgn
• decreased circulating estradiol level_Nhlh2<tm2Thbr>/Nhlh2<tm2Thbr>,Tg(CMV-cre)1Cgn/0
  http://metadb.riken.jp/0005181I129S7SvEvBrdBALBcJC57BL6Nhlh2tm2ThbrNhlh2tm2ThbrTgCMVcre1Cgn0Nhlh2tm2ThbrTgCMVcre1Cgn
他10件を見る
• increased neuron number_Nhlh2<tm1Thbr>/Nhlh2<tm1Thbr>,Tg(Pomc-EGFP)1Low/0
  http://metadb.riken.jp/0008947I129S4SvJaeC57BL6JNhlh2tm1ThbrNhlh2tm1ThbrTgPomcEGFP1Low0TgPomcEGFP1LowNhlh2tm1Thbr
• decreased neuron number_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Tg(Pomc-EGFP)1Low/0,Tg(Gnrh1-cre)1Dlc/0
  http://metadb.riken.jp/0008948I129P2OlaHsdC57BL6C57BL6JCBAGtROSA26Sortm1DTARietGtROSA26SorTgPomcEGFP1Low0TgGnrh1cre1Dlc0GtROSA26Sortm1DTARietGtROSA26SorTgGnrh1cre1DlcTgPomcEGFP1Low
• decreased neuron number_Nhlh2<tm1Thbr>/Nhlh2<tm1Thbr>,Tg(Pomc-EGFP)1Low/0
  http://metadb.riken.jp/0008948I129S4SvJaeC57BL6JNhlh2tm1ThbrNhlh2tm1ThbrTgPomcEGFP1Low0TgPomcEGFP1LowNhlh2tm1Thbr
• decreased neuron number_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Nhlh2<tm2Thbr>/Nhlh2<tm2Thbr>,Tg(Gnrh1-cre)1Dlc/0
  http://metadb.riken.jp/0008948I129S4SvJaeSor129S7SvEvBrdC57BL6CBAGtROSA26Sortm1SorGtROSA26SorNhlh2tm2ThbrNhlh2tm2ThbrTgGnrh1cre1Dlc0TgGnrh1cre1DlcGtROSA26SorGtROSA26Sortm1SorNhlh2tm2Thbr
• decreased neuron number_Nhlh2<tm2Thbr>/Nhlh2<tm2Thbr>,Tg(CMV-cre)1Cgn/0
  http://metadb.riken.jp/0008948I129S7SvEvBrdBALBcJC57BL6Nhlh2tm2ThbrNhlh2tm2ThbrTgCMVcre1Cgn0Nhlh2tm2ThbrTgCMVcre1Cgn
• decreased neuron number_Nhlh2<tm2Thbr>/Nhlh2<tm2Thbr>,Tg(Gnrh1-cre)1Dlc/0,Tg(Pomc-EGFP)1Low/0
  http://metadb.riken.jp/0008948I129S7SvEvBrdC57BL6C57BL6JCBANhlh2tm2ThbrNhlh2tm2ThbrTgGnrh1cre1Dlc0TgPomcEGFP1Low0Nhlh2tm2ThbrTgPomcEGFP1LowTgGnrh1cre1Dlc
• ectopic neuron_Nhlh2<tm1Thbr>/Nhlh2<tm1Thbr>,Tg(Pomc-EGFP)1Low/0
  http://metadb.riken.jp/0011723I129S4SvJaeC57BL6JNhlh2tm1ThbrNhlh2tm1ThbrTgPomcEGFP1Low0TgPomcEGFP1LowNhlh2tm1Thbr
• ectopic neuron_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Nhlh2<tm2Thbr>/Nhlh2<tm2Thbr>,Tg(Gnrh1-cre)1Dlc/0
  http://metadb.riken.jp/0011723I129S4SvJaeSor129S7SvEvBrdC57BL6CBAGtROSA26Sortm1SorGtROSA26SorNhlh2tm2ThbrNhlh2tm2ThbrTgGnrh1cre1Dlc0TgGnrh1cre1DlcGtROSA26SorGtROSA26Sortm1SorNhlh2tm2Thbr
• increased abdominal adipose tissue amount_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Tg(Pomc-EGFP)1Low/0,Tg(Gnrh1-cre)1Dlc/0
  http://metadb.riken.jp/0020411I129P2OlaHsdC57BL6C57BL6JCBAGtROSA26Sortm1DTARietGtROSA26SorTgPomcEGFP1Low0TgGnrh1cre1Dlc0GtROSA26Sortm1DTARietGtROSA26SorTgGnrh1cre1DlcTgPomcEGFP1Low
• increased abdominal adipose tissue amount_Nhlh2<tm2Thbr>/Nhlh2<tm2Thbr>,Tg(CMV-cre)1Cgn/0
  http://metadb.riken.jp/0020411I129S7SvEvBrdBALBcJC57BL6Nhlh2tm2ThbrNhlh2tm2ThbrTgCMVcre1Cgn0Nhlh2tm2ThbrTgCMVcre1Cgn