abnormal positive T cell selection_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0004919I129SvC57BL6DBA2Mapk1tm1HedMapk1tm1HedMapk3tm1GpgMapk3tm1GpgTgCd4cre1Cwi0Mapk1tm1HedTgCd4cre1CwiMapk3tm1Gpg

abnormal positive T cell selection_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mitogen-activated protein kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346858
• mitogen-activated protein kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346859
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mapk1<tm1Hed>/Mapk1<tm1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mapk1<tm1Hed>|Tg(Cd4-cre)1Cwi|Mapk3<tm1Gpg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal positive T cell selection
  http://purl.obolibrary.org/obo/MP_0004919

文献

http://purl.org/net/cito/citesAsAuthority

• April M. Fischer, et.al., The role of erk1 and erk2 in multiple stages of T cell development., Immunity, 2005, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/16226508