April M. Fischer, et.al., The role of erk1 and erk2 in multiple stages of T cell development., Immunity, 2005, 23

http://rdf.ncbi.nlm.nih.gov/pubmed/16226508

April M. Fischer, et.al., The role of erk1 and erk2 in multiple stages of T cell development., Immunity, 2005, 23

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mapk1<tm1.1Hed>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3686888
• Mapk1<tm2Hed>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3686889
• Mapk1<tm1Hed>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3686887

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal positive T cell selection_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0004919IC57BL6DBA2SJLMapk1tm1HedMapk1tm1HedTgTcrAND53Hed0Mapk1tm1HedTgTcrAND53Hed
• abnormal positive T cell selection_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0004919I129SvC57BL6DBA2Mapk1tm1HedMapk1tm1HedMapk3tm1GpgMapk3tm1GpgTgCd4cre1Cwi0Mapk1tm1HedTgCd4cre1CwiMapk3tm1Gpg
• increased double-positive T cell number_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0005091I129SvC57BL6DBA2Mapk1tm1HedMapk1tm1HedMapk3tm1GpgMapk3tm1GpgTgLckcre1Cwi0Mapk1tm1HedTgLckcre1CwiMapk3tm1Gpg
• decreased double-positive T cell number_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0005092IC57BL6DBA2Mapk1tm1HedMapk1tm1HedTgLckcre1Cwi0Mapk1tm1HedTgLckcre1Cwi
• abnormal T cell subpopulation ratio_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(Cd4-cre)1Cwi/0,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0003944I129SvC57BL6DBA2SJLMapk1tm1HedMapk1tm1HedMapk3tm1GpgMapk3tm1GpgTgCd4cre1Cwi0TgTcrAND53Hed0Mapk3tm1GpgTgCd4cre1CwiMapk1tm1HedTgTcrAND53Hed
• decreased CD8-positive, alpha-beta T cell number_Mapk1<tm1.1Hed>/Mapk1<tm1.1Hed>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008079IC57BL6DBA2Mapk1tm11HedMapk1tm11HedTgLckcre1Cwi0TgLckcre1CwiMapk1tm11Hed
• abnormal positive T cell selection_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Tg(Lck-cre)1Cwi/0,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0004919IC57BL6DBA2SJLMapk1tm1HedMapk1tm1HedTgLckcre1Cwi0TgTcrAND53Hed0TgTcrAND53HedMapk1tm1HedTgLckcre1Cwi
• abnormal T cell proliferation_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0005094I129SvC57BL6DBA2Mapk1tm1HedMapk1tm1HedMapk3tm1GpgMapk3tm1GpgTgLckcre1Cwi0Mapk1tm1HedTgLckcre1CwiMapk3tm1Gpg
• decreased CD4-positive, alpha beta T cell number_Mapk1<tm1.1Hed>/Mapk1<tm1.1Hed>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008075IC57BL6DBA2Mapk1tm11HedMapk1tm11HedTgLckcre1Cwi0TgLckcre1CwiMapk1tm11Hed
• decreased CD4-positive, alpha beta T cell number_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008075IC57BL6DBA2Mapk1tm1HedMapk1tm1HedTgCd4cre1Cwi0Mapk1tm1HedTgCd4cre1Cwi
• abnormal positive T cell selection_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(Cd4-cre)1Cwi/0,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0004919I129SvC57BL6DBA2SJLMapk1tm1HedMapk1tm1HedMapk3tm1GpgMapk3tm1GpgTgCd4cre1Cwi0TgTcrAND53Hed0Mapk3tm1GpgTgCd4cre1CwiMapk1tm1HedTgTcrAND53Hed
• increased double-positive T cell number_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005091IC57BL6DBA2Mapk1tm1HedMapk1tm1HedTgCd4cre1Cwi0Mapk1tm1HedTgCd4cre1Cwi
• decreased thymocyte number_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Tg(TcraTcrb)1100Mjb/0
  http://metadb.riken.jp/0000715IC57BL6Mapk1tm1HedMapk1tm1HedTgTcraTcrb1100Mjb0Mapk1tm1HedTgTcraTcrb1100Mjb
• abnormal T cell subpopulation ratio_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Tg(Lck-cre)1Cwi/0,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0003944IC57BL6DBA2SJLMapk1tm1HedMapk1tm1HedTgLckcre1Cwi0TgTcrAND53Hed0TgTcrAND53HedMapk1tm1HedTgLckcre1Cwi
• abnormal positive T cell selection_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0004919IC57BL6DBA2Mapk1tm1HedMapk1tm1HedTgCd4cre1Cwi0Mapk1tm1HedTgCd4cre1Cwi
• decreased thymocyte number_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(TcraTcrb)1100Mjb/0
  http://metadb.riken.jp/0000715I129SvC57BL6Mapk1tm1HedMapk1tm1HedMapk3tm1GpgMapk3tm1GpgTgTcraTcrb1100Mjb0Mapk1tm1HedTgTcraTcrb1100MjbMapk3tm1Gpg
• decreased thymocyte number_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0000715I129SvC57BL6DBA2Mapk1tm1HedMapk1tm1HedMapk3tm1GpgMapk3tm1GpgTgLckcre1Cwi0Mapk1tm1HedTgLckcre1CwiMapk3tm1Gpg
• prenatal lethality, complete penetrance_Mapk1<tm2Hed>/Mapk1<tm2Hed>
  http://metadb.riken.jp/0011091I129S1Sv129X1SvJC57BL6Mapk1tm2HedMapk1tm2HedMapk1tm2Hed
• abnormal T cell subpopulation ratio_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0003944IC57BL6DBA2Mapk1tm1HedMapk1tm1HedTgLckcre1Cwi0Mapk1tm1HedTgLckcre1Cwi
• abnormal T cell subpopulation ratio_Mapk1<tm1.1Hed>/Mapk1<tm1.1Hed>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0003944IC57BL6DBA2Mapk1tm11HedMapk1tm11HedTgLckcre1Cwi0TgLckcre1CwiMapk1tm11Hed
• small thymus_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0000706I129SvC57BL6DBA2Mapk1tm1HedMapk1tm1HedMapk3tm1GpgMapk3tm1GpgTgLckcre1Cwi0Mapk1tm1HedTgLckcre1CwiMapk3tm1Gpg
• abnormal double-positive T cell morphology_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0002408IC57BL6DBA2SJLMapk1tm1HedMapk1tm1HedTgTcrAND53Hed0Mapk1tm1HedTgTcrAND53Hed
• abnormal enzyme/coenzyme level_Mapk1<tm1.1Hed>/Mapk1<tm1.1Hed>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0005319IC57BL6DBA2Mapk1tm11HedMapk1tm11HedTgLckcre1Cwi0TgLckcre1CwiMapk1tm11Hed
• decreased T cell proliferation_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0005095IC57BL6DBA2Mapk1tm1HedMapk1tm1HedTgLckcre1Cwi0Mapk1tm1HedTgLckcre1Cwi
• transmission ratio distortion_Mapk1<tm2Hed>/Mapk1<+>
  http://metadb.riken.jp/0004179I129S1Sv129X1SvJC57BL6Mapk1tm2HedMapk1Mapk1Mapk1tm2Hed
• decreased CD8-positive, alpha-beta T cell number_Mapk1<tm1Hed>/Mapk1<tm1Hed>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008079IC57BL6DBA2Mapk1tm1HedMapk1tm1HedTgCd4cre1Cwi0Mapk1tm1HedTgCd4cre1Cwi

class

http://purl.org/net/cito/citesAsAuthority

• Mapk1<tm1.1Hed>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3686888
• Mapk1<tm2Hed>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3686889
• Mapk1<tm1Hed>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3686887