abnormal regulatory T cell physiology_Foxp3<tm2Ayr>/Foxp3<+>,Rnf128<tm1Cdon>/Rnf128<tm1Cdon>

http://metadb.riken.jp/0004946I129S1Sv129X1SvJC57BL6Foxp3tm2AyrFoxp3Rnf128tm1CdonRnf128tm1CdonFoxp3Foxp3tm2AyrRnf128tm1Cdon

abnormal regulatory T cell physiology_Foxp3<tm2Ayr>/Foxp3<+>,Rnf128<tm1Cdon>/Rnf128<tm1Cdon>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ring finger protein 128
  http://metadb.riken.jp/db/mgi_rdf/MGI:1914139
• forkhead box P3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891436

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxp3<tm2Ayr>/Foxp3<+>,Rnf128<tm1Cdon>/Rnf128<tm1Cdon>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Foxp3<+>|Foxp3<tm2Ayr>|Rnf128<tm1Cdon>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal regulatory T cell physiology
  http://purl.obolibrary.org/obo/MP_0004946

文献

http://purl.org/net/cito/citesAsAuthority

• Roza I. Nurieva, et.al., The E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation., Immunity, 2010, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/20493730