abnormal neuronal precursor proliferation_Atoh1<tm3Hzo>/Atoh1<tm1Hzo>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>

http://metadb.riken.jp/0004948I129129S7SvEvBrd129X1SvJAtoh1tm3HzoAtoh1tm1HzoGtROSA26Sortm1creERTNatGtROSA26Sortm1SmoEYFPAmcAtoh1tm3HzoGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1creERTNatAtoh1tm1Hzo

abnormal neuronal precursor proliferation_Atoh1<tm3Hzo>/Atoh1<tm1Hzo>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• atonal bHLH transcription factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:104654

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Atoh1<tm3Hzo>/Atoh1<tm1Hzo>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Atoh1<tm3Hzo>|Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>|Gt(ROSA)26Sor<tm1(cre/ERT)Nat>|Atoh1<tm1Hzo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S7/SvEvBrd * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal neuronal precursor proliferation
  http://purl.obolibrary.org/obo/MP_0004948

文献

http://purl.org/net/cito/citesAsAuthority

• Adriano. Flora, et.al., Deletion of Atoh1 disrupts Sonic Hedgehog signaling in the developing cerebellum and prevents medulloblastoma., Science (New York, N.Y.), 2009, 326
  http://rdf.ncbi.nlm.nih.gov/pubmed/19965762