abnormal brain vasculature morphology_Ccm2<tm2.1Sbn>/Ccm2<tm2.1Sbn>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0004950IC57BL6CBACcm2tm21SbnCcm2tm21SbnTgMx1cre1Cgn0Ccm2tm21SbnTgMx1cre1Cgn

abnormal brain vasculature morphology_Ccm2<tm2.1Sbn>/Ccm2<tm2.1Sbn>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• cerebral cavernous malformation 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384924

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ccm2<tm2.1Sbn>/Ccm2<tm2.1Sbn>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ccm2<tm2.1Sbn>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal brain vasculature morphology
  http://purl.obolibrary.org/obo/MP_0004950

文献

http://purl.org/net/cito/citesAsAuthority

• Kirk. Cunningham, et.al., Conditional deletion of Ccm2 causes hemorrhage in the adult brain: a mouse model of human cerebral cavernous malformations., Human molecular genetics, 2011, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/21596842