abnormal regulatory T cell number_Foxp3<tm2Ayr>/?,Zap70<rps>/Zap70<rps>

http://metadb.riken.jp/0004972I129S1Sv129X1SvJC57BL6Foxp3tm2AyrZap70rpsZap70rpsZap70rpsFoxp3tm2Ayr

abnormal regulatory T cell number_Foxp3<tm2Ayr>/?,Zap70<rps>/Zap70<rps>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• forkhead box P3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891436
• zeta-chain (TCR) associated protein kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99613

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxp3<tm2Ayr>/?,Zap70<rps>/Zap70<rps>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Zap70<rps>|Foxp3<tm2Ayr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal regulatory T cell number
  http://purl.obolibrary.org/obo/MP_0004972

文献

http://purl.org/net/cito/citesAsAuthority

• Bénédicte. Cauwe, et.al., A novel Zap70 mutation with reduced protein stability demonstrates the rate-limiting threshold for Zap70 in T-cell receptor signalling., Immunology, 2014, 141
  http://rdf.ncbi.nlm.nih.gov/pubmed/24164480