Bénédicte. Cauwe, et.al., A novel Zap70 mutation with reduced protein stability demonstrates the rate-limiting threshold for Zap70 in T-cell receptor signalling., Immunology, 2014, 141

http://rdf.ncbi.nlm.nih.gov/pubmed/24164480

Bénédicte. Cauwe, et.al., A novel Zap70 mutation with reduced protein stability demonstrates the rate-limiting threshold for Zap70 in T-cell receptor signalling., Immunology, 2014, 141

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Zap70<rps>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5576549

class

http://purl.org/net/cito/citesAsAuthority

• Zap70<rps>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5576549

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal T cell differentiation_Foxp3<tm2Ayr>/?,Zap70<rps>/Zap70<rps>
  http://metadb.riken.jp/0002145I129S1Sv129X1SvJC57BL6Foxp3tm2AyrZap70rpsZap70rpsZap70rpsFoxp3tm2Ayr
• abnormal double-positive T cell morphology_Foxp3<tm2Ayr>/?,Zap70<rps>/Zap70<rps>
  http://metadb.riken.jp/0002408I129S1Sv129X1SvJC57BL6Foxp3tm2AyrZap70rpsZap70rpsZap70rpsFoxp3tm2Ayr
• abnormal double-positive T cell morphology_Zap70<mrtle>/Zap70<mrtle>
  http://metadb.riken.jp/0002408IC57BL6JSfdAnuZap70mrtleZap70mrtleZap70mrtle
• abnormal CD4-positive, alpha beta T cell morphology_Foxp3<tm2Ayr>/?,Zap70<rps>/Zap70<rps>
  http://metadb.riken.jp/0002432I129S1Sv129X1SvJC57BL6Foxp3tm2AyrZap70rpsZap70rpsZap70rpsFoxp3tm2Ayr
• decreased CD4-positive, alpha beta T cell number_Zap70<mrtle>/Zap70<rps>
  http://metadb.riken.jp/0008075IC57BL6C57BL6JSfdAnuZap70mrtleZap70rpsZap70rpsZap70mrtle
• abnormal double-positive T cell morphology_Zap70<mrtle>/Zap70<rps>
  http://metadb.riken.jp/0002408IC57BL6C57BL6JSfdAnuZap70mrtleZap70rpsZap70rpsZap70mrtle
• decreased CD4-positive, alpha beta T cell number_Zap70<mrtle>/Zap70<mrtle>
  http://metadb.riken.jp/0008075IC57BL6JSfdAnuZap70mrtleZap70mrtleZap70mrtle
• decreased CD4-positive, alpha beta T cell number_Foxp3<tm2Ayr>/?,Zap70<rps>/Zap70<rps>
  http://metadb.riken.jp/0008075I129S1Sv129X1SvJC57BL6Foxp3tm2AyrZap70rpsZap70rpsZap70rpsFoxp3tm2Ayr
• increased double-positive T cell number_Zap70<mrtle>/Zap70<mrtle>
  http://metadb.riken.jp/0005091IC57BL6JSfdAnuZap70mrtleZap70mrtleZap70mrtle
• abnormal regulatory T cell number_Zap70<mrtle>/Zap70<mrtle>
  http://metadb.riken.jp/0004972IC57BL6JSfdAnuZap70mrtleZap70mrtleZap70mrtle
• decreased CD8-positive, alpha-beta T cell number_Foxp3<tm2Ayr>/?,Zap70<rps>/Zap70<rps>
  http://metadb.riken.jp/0008079I129S1Sv129X1SvJC57BL6Foxp3tm2AyrZap70rpsZap70rpsZap70rpsFoxp3tm2Ayr
• abnormal CD4-positive, alpha beta T cell morphology_Zap70<mrtle>/Zap70<rps>
  http://metadb.riken.jp/0002432IC57BL6C57BL6JSfdAnuZap70mrtleZap70rpsZap70rpsZap70mrtle
• decreased CD8-positive, alpha-beta T cell number_Zap70<mrtle>/Zap70<mrtle>
  http://metadb.riken.jp/0008079IC57BL6JSfdAnuZap70mrtleZap70mrtleZap70mrtle
• abnormal regulatory T cell number_Zap70<mrtle>/Zap70<rps>
  http://metadb.riken.jp/0004972IC57BL6C57BL6JSfdAnuZap70mrtleZap70rpsZap70rpsZap70mrtle
• increased double-positive T cell number_Zap70<mrtle>/Zap70<rps>
  http://metadb.riken.jp/0005091IC57BL6C57BL6JSfdAnuZap70mrtleZap70rpsZap70rpsZap70mrtle
• decreased CD8-positive, alpha-beta T cell number_Zap70<mrtle>/Zap70<rps>
  http://metadb.riken.jp/0008079IC57BL6C57BL6JSfdAnuZap70mrtleZap70rpsZap70rpsZap70mrtle
• abnormal regulatory T cell number_Foxp3<tm2Ayr>/?,Zap70<rps>/Zap70<rps>
  http://metadb.riken.jp/0004972I129S1Sv129X1SvJC57BL6Foxp3tm2AyrZap70rpsZap70rpsZap70rpsFoxp3tm2Ayr