increased regulatory T cell number_Fyn<tm1Sor>/Fyn<tm1Sor>,Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>

http://metadb.riken.jp/0004973I129S7SvEvBrd129X1SvJFyntm1SorFyntm1SorLcktm1LittLcktm11LittTnfrsf4tm2creNikTnfrsf4Lcktm11LittFyntm1SorTnfrsf4tm2creNikTnfrsf4Lcktm1Litt

increased regulatory T cell number_Fyn<tm1Sor>/Fyn<tm1Sor>,Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tumor necrosis factor receptor superfamily, member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:104512
• Fyn proto-oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:95602
• lymphocyte protein tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96756

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fyn<tm1Sor>/Fyn<tm1Sor>,Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lck<tm1.1Litt>|Fyn<tm1Sor>|Tnfrsf4<tm2(cre)Nik>|Tnfrsf4<+>|Lck<tm1Litt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased regulatory T cell number
  http://purl.obolibrary.org/obo/MP_0004973

文献

http://purl.org/net/cito/citesAsAuthority

• Joong Kyu. Kim, et.al., Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking., PloS one, 2009, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/19668367