Joong Kyu. Kim, et.al., Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking., PloS one, 2009, 4

http://rdf.ncbi.nlm.nih.gov/pubmed/19668367

Joong Kyu. Kim, et.al., Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking., PloS one, 2009, 4

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lck<tm1.1Litt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4358985
• Lck<tm1Litt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4358983

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal regulatory T cell physiology_Fyn<tm1Sor>/Fyn<tm1Sor>,Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0004946I129S7SvEvBrd129X1SvJFyntm1SorFyntm1SorLcktm1LittLcktm11LittTnfrsf4tm2creNikTnfrsf4Lcktm11LittFyntm1SorTnfrsf4tm2creNikTnfrsf4Lcktm1Litt
• decreased T cell proliferation_Fyn<tm1Sor>/Fyn<tm1Sor>,Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0005095I129S7SvEvBrd129X1SvJFyntm1SorFyntm1SorLcktm1LittLcktm11LittTnfrsf4tm2creNikTnfrsf4Lcktm11LittFyntm1SorTnfrsf4tm2creNikTnfrsf4Lcktm1Litt
• increased regulatory T cell number_Fyn<tm1Sor>/Fyn<tm1Sor>,Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0004973I129S7SvEvBrd129X1SvJFyntm1SorFyntm1SorLcktm1LittLcktm11LittTnfrsf4tm2creNikTnfrsf4Lcktm11LittFyntm1SorTnfrsf4tm2creNikTnfrsf4Lcktm1Litt
• increased T cell number_Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0005015I129X1SvJLcktm1LittLcktm11LittTnfrsf4tm2creNikTnfrsf4Lcktm11LittLcktm1LittTnfrsf4Tnfrsf4tm2creNik
• abnormal thymus morphology_Lck<tm1.1Litt>/Lck<tm1.1Litt>
  http://metadb.riken.jp/0000703NSLcktm11LittLcktm11LittLcktm11Litt
• abnormal lymphocyte morphology_Lck<tm1.1Litt>/Lck<tm1.1Litt>
  http://metadb.riken.jp/0002619NSLcktm11LittLcktm11LittLcktm11Litt
• abnormal regulatory T cell physiology_Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0004946I129X1SvJLcktm1LittLcktm11LittTnfrsf4tm2creNikTnfrsf4Lcktm11LittLcktm1LittTnfrsf4Tnfrsf4tm2creNik
• decreased regulatory T cell number_Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0004974I129X1SvJLcktm1LittLcktm11LittTnfrsf4tm2creNikTnfrsf4Lcktm11LittLcktm1LittTnfrsf4Tnfrsf4tm2creNik
• decreased regulatory T cell number_Fyn<tm1Sor>/Fyn<tm1Sor>,Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0004974I129S7SvEvBrd129X1SvJFyntm1SorFyntm1SorLcktm1LittLcktm11LittTnfrsf4tm2creNikTnfrsf4Lcktm11LittFyntm1SorTnfrsf4tm2creNikTnfrsf4Lcktm1Litt
• increased regulatory T cell number_Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0004973I129X1SvJLcktm1LittLcktm11LittTnfrsf4tm2creNikTnfrsf4Lcktm11LittLcktm1LittTnfrsf4Tnfrsf4tm2creNik
• increased T cell number_Fyn<tm1Sor>/Fyn<tm1Sor>,Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0005015I129S7SvEvBrd129X1SvJFyntm1SorFyntm1SorLcktm1LittLcktm11LittTnfrsf4tm2creNikTnfrsf4Lcktm11LittFyntm1SorTnfrsf4tm2creNikTnfrsf4Lcktm1Litt
• abnormal regulatory T cell physiology_Cd4<tm1Nik>/Cd4<tm1Nik>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0004946I129X1SvJCd4tm1NikCd4tm1NikTnfrsf4tm2creNikTnfrsf4Cd4tm1NikTnfrsf4Tnfrsf4tm2creNik
• abnormal immunoglobulin level_Lck<tm1.1Litt>/Lck<tm1.1Litt>
  http://metadb.riken.jp/0002490NSLcktm11LittLcktm11LittLcktm11Litt
• enlarged lymph nodes_Fyn<tm1Sor>/Fyn<tm1Sor>,Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0000702I129S7SvEvBrd129X1SvJFyntm1SorFyntm1SorLcktm1LittLcktm11LittTnfrsf4tm2creNikTnfrsf4Lcktm11LittFyntm1SorTnfrsf4tm2creNikTnfrsf4Lcktm1Litt
• decreased T cell proliferation_Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0005095I129X1SvJLcktm1LittLcktm11LittTnfrsf4tm2creNikTnfrsf4Lcktm11LittLcktm1LittTnfrsf4Tnfrsf4tm2creNik
• enlarged lymph nodes_Lck<tm1Litt>/Lck<tm1.1Litt>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0000702I129X1SvJLcktm1LittLcktm11LittTnfrsf4tm2creNikTnfrsf4Lcktm11LittLcktm1LittTnfrsf4Tnfrsf4tm2creNik

class

http://purl.org/net/cito/citesAsAuthority

• Lck<tm1.1Litt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4358985
• Lck<tm1Litt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4358983