decreased regulatory T cell number_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0004974I129C57BL6DBA2Dicer1tm1BdhDicer1tm1BdhTgCd4cre1Cwi0TgCd4cre1CwiDicer1tm1Bdh

decreased regulatory T cell number_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688
• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Dicer1<tm1Bdh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased regulatory T cell number
  http://purl.obolibrary.org/obo/MP_0004974

文献

http://purl.org/net/cito/citesAsAuthority

• Mark M W. Chong, et.al., The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease., The Journal of experimental medicine, 2008, 205
  http://rdf.ncbi.nlm.nih.gov/pubmed/18725527