decreased B-1 B cell number_Fnip1<tm1.2Baba>/Fnip1<tm1.2Baba>,Tg(IghelMD4)4Ccg/0

http://metadb.riken.jp/0004978IC57BL6C57BL6JFVBNSJLFnip1tm12BabaFnip1tm12BabaTgIghelMD44Ccg0Fnip1tm12BabaTgIghelMD44Ccg

decreased B-1 B cell number_Fnip1<tm1.2Baba>/Fnip1<tm1.2Baba>,Tg(IghelMD4)4Ccg/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• folliculin interacting protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2444668
• transgene insertion 4, Christopher C Goodnow
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fnip1<tm1.2Baba>/Fnip1<tm1.2Baba>,Tg(IghelMD4)4Ccg/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fnip1<tm1.2Baba>|Tg(IghelMD4)4Ccg

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6J * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B-1 B cell number
  http://purl.obolibrary.org/obo/MP_0004978

文献

http://purl.org/net/cito/citesAsAuthority

• Masaya. Baba, et.al., The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development., Blood, 2012, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/22709692