increased neuronal precursor cell number_Huwe1<tm1Alas>/Y,Tg(Nes-cre)1Kag/0

http://metadb.riken.jp/0004980I129S7SvEvBrdHuwe1tm1AlasYTgNescre1Kag0Huwe1tm1AlasTgNescre1Kag

increased neuronal precursor cell number_Huwe1<tm1Alas>/Y,Tg(Nes-cre)1Kag/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• HECT, UBA and WWE domain containing 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926884
• transgene insertion 1, Ryoichiro Kageyama
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176221

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Huwe1<tm1Alas>/Y,Tg(Nes-cre)1Kag/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Huwe1<tm1Alas>|Tg(Nes-cre)1Kag

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased neuronal precursor cell number
  http://purl.obolibrary.org/obo/MP_0004980

文献

http://purl.org/net/cito/citesAsAuthority

• Xudong. Zhao, et.al., The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain., Developmental cell, 2009, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/19686682