decreased osteoclast cell number_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Runx2-rtTA*M2)#Flng/0,Tg(tetO-cre)1Jaw/0

http://metadb.riken.jp/0004985I129C57BL6GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgRunx2rtTAM2Flng0TgtetOcre1Jaw0GtROSA26SorTgtetOcre1JawTgRunx2rtTAM2FlngGtROSA26Sortm4Wnt7bFlng

decreased osteoclast cell number_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Runx2-rtTA*M2)#Flng/0,Tg(tetO-cre)1Jaw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Fanxin Long
  http://metadb.riken.jp/db/mgi_rdf/MGI:5613579
• transgene insertion 1, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:3028584
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Runx2-rtTA*M2)#Flng/0,Tg(tetO-cre)1Jaw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Tg(tetO-cre)1Jaw|Tg(Runx2-rtTA*M2)#Flng|Gt(ROSA)26Sor<tm4(Wnt7b)Flng>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased osteoclast cell number
  http://purl.obolibrary.org/obo/MP_0004985

文献

http://purl.org/net/cito/citesAsAuthority

• Jianquan. Chen, et.al., WNT7B promotes bone formation in part through mTORC1., PLoS genetics, 2014, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/24497849